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Longevity Treatments

Compounded Longevity Treatments at Massey Drugs

Longevity treatments like NAD+, Low Dose Naltrexone (LDN), Sermorelin, and others are gaining popularity for their potential to support energy, immunity, mood, metabolism, and more. You’ve likely seen ads from telehealth companies offering these treatments—but what many people don’t realize is that these same medications can be compounded locally by your trusted compounding pharmacy. At Massey Drugs, we prepare high-quality, custom formulations of these treatments in our Alabama-based, NABP-accredited 503A compounding pharmacy. Whether you’re exploring treatments with your doctor or looking for an alternative to online clinics, we’re here to help you access these treatments conveniently and locally. Live outside Alabama? We ship to additional states including: GA, LA, MS, FL, TN, KY, SC, NC, OH, IL, IN, PA and NY. 

Low Dose Naltrexone (LDN)

What is LDN?

LDN stands for Low Dose Naltrexone. Originally developed in higher doses to treat opioid addiction, LDN is now used off-label in much lower doses for its potential to regulate immune function and reduce inflammation.

LDN may:

  • Lower ESR (erythrocyte sedimentation rate), a marker of inflammation in the body
  • Increase natural endorphin levels
  • Reduce chronic pain
  • Reduce fatigue and brain fog
  • Improve overall mood and feeling of well-being
  • Reduce food cravings
  • Encourage weight loss
  • Reduce chance of autoimmunity
  • Modulate the immune system

LDN is taken as a compounded oral capsule or sublingual suspension (under the tongue), typically once daily at bedtime.

LDN is generally well-tolerated. Some patients may experience:

  • Vivid dreams

  • Headache

  • Nausea or GI discomfort (usually mild)


These effects typically resolve within the first few days of use.

Patients with:

  • Autoimmune or inflammatory conditions

  • Chronic pain

  • Neurological or fatigue-related disorders

  • A desire for non-opioid, non-stimulant support

Your doctor can determine if LDN is appropriate for your situation.

Prices vary depending on dose and quantity. Most LDN capsules and sublingual suspensions are affordable (about $1.70/dose), and our team can provide the price once we receive the prescription. 

NAD+ Injection (Nicotinamide Adenine Dinucleotide)

What is NAD+?

NAD+ is a coenzyme found in every cell of the body, essential for converting food into energy and supporting DNA repair, cellular metabolism, and brain function. NAD+ levels naturally decline with age, which may contribute to fatigue, cognitive changes, and slower recovery.

NAD+ is commonly used to support:

  • Energy production and endurance

  • Brain clarity and focus

  • Healthy aging and mitochondrial health

  • Detoxification and cellular repair

Addiction recovery protocols (in higher doses)

At Massey Drugs, NAD+ is compounded into a subcutaneous injection. Injections are typically given several times a week. (We need to be specific here if we can (i.e. 3 times a week). 

NAD+ may: 

  • Increase daily energy and vitality

  • Improve mental clarity and focus

  • Result in faster workout recovery

  • Enhance cellular repair and detoxification

Improve mood and resilience to stress

NAD+ is generally well-tolerated. Possible mild effects may include:

  • Headache

  • Flushing or warmth (especially with injections)

  • Nausea or upset stomach (rare)

Most side effects are short-lived and dose-related.

  • Adults experiencing fatigue, brain fog, or slow recovery

  • Those pursuing healthy aging and wellness optimization

  • Patients under high physical or mental stress

  • Individuals recovering from chronic illness or burnout

Most NAD+ treatments are not covered by insurance. The standard price for NAD+ injection is $130 for a 30-day supply. 

Sermorelin Acetate

What is Sermorelin Acetate?

Sermorelin Acetate is a synthetic peptide that stimulates the body’s natural production of growth hormone by mimicking growth hormone–releasing hormone (GHRH). Unlike synthetic HGH, it works with your endocrine system to support balanced, natural hormone levels.

Sermorelin Acetate may be prescribed to help with:

  • Symptoms of growth hormone deficiency

  • Muscle recovery and preservation of lean body mass

  • Improved sleep quality and mood

  • Fat metabolism and weight management

  • Anti-aging and vitality support

 Massey Drugs compounds Sermorelin Acetate as:

  • Sublingual suspension – placed under the tongue daily for easy use
  • Injectable form – administered as directed by your provider

Potential benefits may include:

  • Deeper, more restorative sleep

  • Improved energy and mood

  • Enhanced muscle tone and faster recovery

  • Fat reduction, especially in the midsection

  • Increased vitality and mental clarity

Sermorelin Acetate  is generally well-tolerated. Possible side effects can include:

  • Temporary redness, swelling, or discomfort at injection site (injectable form)

  • Mild flushing or dizziness

  • Increased hunger or vivid dreams

  • Occasional headache


Most side effects are mild and often resolve with dose adjustment.

  • Adults with symptoms of low growth hormone (fatigue, poor sleep, reduced recovery)

  • Men and women in midlife seeking anti-aging or performance support

  • Individuals looking for a safer alternative to synthetic HGH


A provider will confirm candidacy through lab work and symptom evaluation.

 Sermorelin Acetate may not be appropriate for:

  • Individuals with active cancer or a history of certain hormone-sensitive cancers

  • Those with untreated hypothyroidism or uncontrolled diabetes

  • Pregnant or breastfeeding women

  • Anyone allergic to Sermorelin or its ingredients


Your healthcare provider should review your full medical history before starting therapy.

Sermorelin Acetate is typically not covered by insurance. Costs vary by dose and form:

  • Injectable: around $150/month

  • Sublingual suspension: pricing provided upon prescription review
    Massey Drugs will provide a detailed quote once your prescription is received.
Longevity Treatments

Hydroxocobalamin (Vitamin B12 Injection)

What is Hydroxocobalamin?

Hydroxocobalamin is a long-acting form of Vitamin B12, a vital nutrient involved in energy production, nerve function, red blood cell formation, and DNA synthesis. Unlike the more common cyanocobalamin, hydroxocobalamin stays in the body longer and may be more effective for correcting B12 deficiencies.

Hydroxocobalamin is commonly prescribed to support:

  • Vitamin B12 deficiency

  • Fatigue or low energy

  • Anemia and neurological symptoms

  • Brain fog or poor concentration

  • Mood support and immune health

  • Methylation and detoxification pathways

Hydroxocobalamin is compounded as a sterile intramuscular (IM) or subcutaneous (SQ) injection. Most providers recommend once-weekly injections to restore and maintain optimal B12 levels.

B12 injections may result in:

  • Increased energy and stamina

  • Improved mental clarity

  • Enhanced mood and motivation

  • Reduction in numbness or tingling

  • Better sleep and immune resilience

Possible mild side effects include:

  • Injection site soreness or redness

  • Headache or dizziness (rare)

  • Mild flushing

Hydroxocobalamin is considered safer than cyanocobalamin for long-term use, especially for individuals with methylation issues.

  • Adults with fatigue, low energy, or brain fog

  • People with low B12 due to diet (e.g., vegetarians, vegans)

  • Patients with GI conditions (e.g., Crohn’s, gastric bypass) affecting absorption

  • Anyone with lab-confirmed B12 deficiency

  • Those looking to support neurological or immune health

Vitamin B12 injections are affordable and often not covered by insurance. Pricing can run as much as $50/vial. 

Rapamycin (Sirolimus)

What is Rapamycin?

Rapamycin, also known as Sirolimus, is an immunosuppressant originally approved to prevent organ transplant rejection. In recent years, it’s gained interest in the longevity field for its potential to slow biological aging by inhibiting the mTOR pathway—a key regulator of cell growth, metabolism, and senescence.

Research suggests Rapamycin may:

  • Support healthy aging by modulating mTOR activity

  • Delay onset of age-related diseases

  • Reduce markers of cellular senescence

  • Improve metabolic markers (glucose, insulin sensitivity, etc.)

  • Enhance autophagy (cellular cleanup)

  • Improve immune function in older adults

Rapamycin is taken orally, typically once weekly, in capsule form. The dose and schedule are personalized and determined by a prescribing provider.

At low, intermittent doses used in longevity medicine, Rapamycin is generally well-tolerated. Possible side effects may include:

  • Mouth sores

  • GI upset

  • Elevated cholesterol or triglycerides

  • Temporary immune suppression

Close monitoring by your provider can help manage and minimize risks.

Patients who are:

  • Interested in evidence-based longevity strategies

  • Looking to improve biological resilience and cellular health

  • Under the care of a provider knowledgeable in age management medicine

Rapamycin is not for everyone—especially those with active infections, immune disorders, or uncontrolled diabetes. Your doctor will determine if it’s right for you.

Pricing varies based on strength and quantity. A month’s supply starts at $5/capsule or $20/month if taken once a week.

Methylene Blue

What is Methylene Blue?

Methylene Blue is a synthetic compound with antioxidant and mitochondrial-supportive properties. Originally developed for medical and laboratory use, it is now being studied and used off-label in low doses for its potential cognitive, energy, and neuroprotective benefits.

 Methylene Blue may be prescribed or recommended for:

  • Cognitive support and mental clarity

  • Mitochondrial health and energy production

  • Support in certain neurological conditions

  • Antioxidant and anti-inflammatory benefits

  • Adjunctive therapy in integrative and longevity programs

Massey Drugs compounds Methylene Blue as oral capsules in 5mg, 15mg, and 25mg strengths for convenient daily use. Your provider will determine the appropriate dose for your needs.

 Potential benefits may include:

  • Enhanced mental focus and clarity

  • Increased cellular energy production

  • Support for mood and motivation

  • Antioxidant protection against oxidative stress

  • Potential neuroprotective effects

Methylene Blue is generally well-tolerated at low doses. Possible side effects may include:

  • Blue or green discoloration of urine or stool (harmless)

  • Mild gastrointestinal upset

  • Headache or dizziness

  • Serotonin syndrome risk if combined with certain antidepressants (SSRIs, SNRIs, MAOIs)


Your provider should review all current medications to prevent interactions.

 

  • Adults seeking cognitive or energy support

  • Individuals interested in longevity and mitochondrial health programs

  • Patients under physician supervision for neurological or metabolic concerns

Methylene Blue may not be appropriate for:

  • Pregnant or breastfeeding women

     

  • Individuals with known hypersensitivity to Methylene Blue

     

  • Patients taking serotonergic medications (unless directed and monitored by a provider)

     

  • Those with G6PD deficiency or certain blood disorders

Massey Drugs offers Methylene Blue capsules starting at $2.25 per capsule, with pricing depending on strength and quantity. A detailed quote will be provided once your prescription is received.

How do I get one or more of these Longevity Treatments?

All of our compounded longevity treatments—such as NAD+, Low Dose Naltrexone, Sermorelin, Hydroxocobalamin (B12), Rapamycin and Methylene Blue—require a prescription from a licensed healthcare provider. If you and your doctor decide that one of these treatments may be appropriate, simply ask them to send your prescription to Massey Drugs.

It’s easy to get started:

  1. Discuss your symptoms or goals with your physician.

     

  2. Ask if one or more of these longevity compounds might be right for you.

     

  3. Have your provider send the prescription to Massey Drugs (Fax: 800.637.2601).

     

  4. Once we receive the prescription, we’ll compound your medication and ship it directly to your home within 24–48 hours or you can pick it up at our Cloverdale store.

     

Need help explaining to your doctor? We’re happy to provide an information sheet or consult directly with your provider.

How do I get a refill? 
When it’s time to refill, give us a call and we can contact your provider. Or, you can call your provider and they can send us a request for a refill. 

Why choose your doctor and Massey Drugs instead of buying online?

You’ve probably seen ads from online wellness or telehealth companies offering these same treatments—but what some don’t tell you is where the medication comes from, who makes it, or what it actually costs long term.

When you work with your own provider and Massey Drugs, you get:

  • Personalized Care: Your doctor knows your full health history and can tailor therapy to your needs.

     

  • Faster Access to Your Treatment: Same- or next-day pickup available, or shipping to your door in just 24–48 hours from receiving your prescription from your provider.

     

  • Quality Compounding: We are the Shoals only NABP-accredited compounding pharmacy and one of five in Alabama.

     

  • Real Pharmacist Support: Just give us a call to speak directly with a licensed Alabama pharmacist, not a call center or online bot.

     

Choosing Massey Drugs means choosing trusted, personalized care—without sacrificing quality, convenience or customer care.

Ready to Get Started?

Talk to your doctor about whether one of these compounded longevity treatments is right for you. Once your prescription is sent to Massey Drugs, we’ll compound it with care, ship it directly to your door or have it ready for in-store pick up at our Cloverdale location.