Chronic and acute pain conditions often require individualized treatment approaches that commercially available medications cannot fully address. Compounded pain management medications allow prescribers to customize active ingredients, strengths, and dosage forms to better match each patient’s clinical needs.
At Massey Drugs, we work closely with pain specialists, primary care providers, dermatologists, otolaryngologists, neurologists, and other prescribers to prepare high-quality compounded pain and topical anesthetic medications. Our pharmacist team collaborates directly with providers to help optimize formulations while maintaining our fast 24–48 hour turnaround and reliable shipping across our licensed states.
Whether the goal is neuropathic pain relief, musculoskeletal support, or localized numbing, compounded therapies can offer valuable flexibility when standard options are insufficient or poorly tolerated.
What Are Compounded Pain Management Medications?
Compounded pain and numbing medications may be prescribed for a wide range of conditions, including:
- Neuropathic pain
- Musculoskeletal pain
- Joint and arthritis discomfort
- Post-procedure or localized pain
- Pelvic or vulvar discomfort
- Sports injuries and soft tissue pain
- Peripheral neuropathy
- Localized skin sensitivity requiring topical anesthesia
Prescribers often choose compounded topicals to help deliver medication directly to the affected area while potentially reducing systemic exposure.
Available Pain and Numbing Compounded Preparations
Massey Drugs compounds customized pain management and topical anesthetic medications pursuant to a valid prescription. Current formulations available on our prescribing blanks include:
Topical Numbing and Anesthetic Preparations
- Lidocaine 23% / Tetracaine 7% Plasticized Ointment
- Benzocaine 20% / Lidocaine 6% / Tetracaine 4% Lipoderm Cream
- Lidocaine 3% / Tetracaine 3% Washable Gel
Neuropathic Pain and Multi-Mechanism Topical Gels
- DBGL — Diclofenac Na 5% / Baclofen 3% / Gabapentin 5% / Lidocaine 5% Transdermal Gel
Diclofenac Na 1.5% / Lidocaine 2.5% / Prilocaine 2.5% Transdermal Gel
Gabapentin 3% / Diclofenac Na 1.5% / Lidocaine 2.5% / Prilocaine 2.5% Transdermal Gel
- Ketamine HCl 10% / Gabapentin 6% / Lidocaine 5% / Baclofen 2% / Cyclobenzaprine HCl 2% Transdermal Gel
- Ketamine HCl 10% / Gabapentin 3% / Diclofenac Na 1.5% / Lidocaine 2.5% / Prilocaine 2.5% Transdermal Gel
- Acyclovir 5% / Ketoprofen 5% / Amitriptyline HCl 2% / Tetracaine 1% Transdermal Gel
ENT Office-Based Anesthetic Compounds
ENT compounds typically used by ENT specialists to provide localized mucosal anesthesia during in-office procedures.
- CMPD Tetracaine HCl 6% Nasal Gel (10 g)
- CMPD Tetracaine HCl 0.5% Lollipop
- CMPD Tetracaine HCl 0.5% Throat Spray (30 mL)
Women’s Health Pain and Pelvic Comfort Preparations
Women’s health compounds may be prescribed for pelvic floor dysfunction, vaginal discomfort, or procedure-related numbing.
- Lidocaine 23% / Tetracaine 7% Anhydrous Vaginal Ointment
- Diazepam 5 mg / Cyclobenzaprine HCl 10 mg per gram Anhydrous Vaginal Ointment
- Diazepam 10 mg per gram Anhydrous Vaginal Ointment
Benefits of Compounded Pain Therapy
Compounded medications can offer several clinical advantages when used under appropriate medical supervision:
- Targeted therapy
Topical delivery allows medication to be applied directly where needed. - Customization
Strengths and ingredient combinations can be tailored to the individual patient. - Combination therapy
Multiple active ingredients may be incorporated into a single preparation when clinically appropriate. - Alternative dosage forms
Options beyond standard tablets or capsules may improve patient adherence. - Allergen avoidance
Formulations can often be prepared without certain dyes, preservatives, or excipients when necessary.
Who May Benefit from Compounded Pain Medications?
Prescribers may consider compounded pain or numbing medications for patients who:
- Have inadequate relief from commercially available products
- Experience side effects with oral medications
- Require multi-mechanism pain management
- Need localized therapy
- Have sensitivities to ingredients in manufactured products
- Require specialized topical anesthetic support
Why Physicians Trust Massey Drugs
Healthcare providers need a compounding partner that delivers consistent quality, fast turnaround, and a smooth patient experience. Massey Drugs is built to support providers and patients with reliable formulations and responsive pharmacy support.
What clinics value most:
- High-quality compounded medications prepared under strict standards
- Fast, reliable 24–48 hour shipping
- Direct-to-patient or direct-to-clinic delivery
- Clear, easy-to-follow patient instructions included with medications
- Competitive, clinic-friendly pricing
- Direct pharmacist access when prescribers and patients need support
- NABP Accredited Pharmacy
States We Serve
Massey Drugs is a 503A, NABP accredited compounding pharmacy licensed to ship compounds to patients in:
Alabama, Mississippi, Tennessee, Georgia, Kentucky, Illinois, Florida, North Carolina, Ohio, Pennsylvania, New York, Louisiana, South Carolina, Indiana, Texas, and Connecticut.
How to Prescribe
Download Rx Blank from the Practitioner Portal and send to Massey Drugs:
FAX: 800.637.2601
Phone: 833.540.3500
OR
e-Scribe: NPI#: 1295756245 | NCPCP#: 0127553
Massey Drugs | Cloverdale Road
Upon receipt of prescription, Massey Drugs contacts the patient to confirm shipping address and credit card payment.
Medication ships to patient in 24-48 hours
once processed.
Massey Drugs provides competitively priced compounded medications with transparent, prescriber-accessible pricing. All compound pricing can be viewed in our Practitioner Portal so costs can be communicated to patients before prescribing.
Speak with a Pharmacist
If you have questions about compounded pain or numbing medications, our pharmacists are available to consult. Call 833-540-3500 or contact us.
Frequently Asked Questions
Are compounded pain creams the same as over-the-counter topicals?
No. Compounded pain creams are prescription medications prepared in customized strengths and ingredient combinations that are not available in standard OTC products.
Do topical pain medications enter the bloodstream?
Some systemic absorption may occur depending on the ingredients and base used. However, many compounded topicals are designed to provide more localized therapy compared to oral medications.
How long does it take to feel relief?
Onset varies based on the formulation, condition being treated, and individual patient response. Prescribers typically provide guidance on expected timelines.