Semaglutide Sublingual Suspension: A Non-Injectable Option for GLP-1 Therapy
Massey Drugs compounds Semaglutide 2mg/mL Sublingual Suspension in SubMagna™ HMW, designed for daily administration under the tongue—ideal for people who prefer to avoid injections or who are on maintenance. This formulation allows compounded Semaglutide to be absorbed via the sublingual or under the tongue route, bypassing the gastrointestinal tract and offering a needle-free alternative for appropriate patients.
Frequently Asked Questions: Semaglutide Sublingual Suspension
Understanding the Medication
What is Semaglutide Sublingual Suspension?
A compounded formulation of semaglutide designed for daily administration under the tongue.
Why is this medication compounded?
Compounded medications are custom-prepared by a compounding pharmacy when commercial options don’t meet a patient’s individual needs—such as delivery method, ingredients, dosage or availability.
How is it different from the injectable version?
This formulation is compounded as a suspension for sublingual (under-the-tongue) use rather than subcutaneous injection. Your provider can help determine if this delivery method is appropriate for you.
Who might consider a sublingual alternative?
Patients who prefer not to use injections or are exploring non-injectable options for GLP-1 maintenance therapy may ask their provider about sublingual formulations.
Prescribing & Usage
What should be considered before taking this compounded medication?
Be sure to tell your healthcare provider about all of your medical conditions and medications. This is especially important if you have a history of thyroid, pancreatic, or kidney disease (including any related cancers, even in family members), diabetic eye disease (such as retinopathy), or mental health conditions like depression or suicidal thoughts. You should also inform your provider if you are pregnant, planning to become pregnant, breastfeeding, or using insulin or other diabetes medications.
What should I discuss with my provider?
Ask whether a sublingual formulation is a potential option for your treatment plan and whether it fits your health history and goals.
Do I need a prescription?
Yes. Compounded medications can only be dispensed with a prescription from a licensed healthcare provider.
How is this medication taken?
Semaglutide Sublingual is taken once daily by placing a measured dose under the tongue. The suspension should be shaken well before each use. Using an oral syringe, the prescribed dose is withdrawn and placed under the tongue, where it should be held for at least 90 seconds before swallowing. Patients are typically advised to wait at least 30 minutes after dosing before eating or drinking.
How should I store it?
Storage instructions will be provided with the prescription. Typically, compounded suspensions are stored at room temperature in an amber prescription bottle.
What are common side effects?
Common side effects may include:
- Nausea, vomiting, and diarrhea
- Abdominal pain
- Constipation
Access & Cost
How much does it cost?
The patient price for Semaglutide Sublingual is $165 for a one-month supply (30-day supply based on typical 2mg (1mL) daily maintenance dose). Insurance typically does not pay for this medication. Clinics can register for the Practitioner Portal for clinic pricing and prescription blanks.
How can I get this compounded medication?
Talk to your healthcare provider to see if Semaglutide Sublingual is right for you. Your provider will need to send a prescription to Massey Drugs. Once we receive your prescription, your medication will be filled and can be picked up in store or shipped to your home in a state that Massey Drugs is licensed in. Our licensed states include: AL, TN, MS, LA, FL, GA, KY, IN, IL, OH, PA, NY, SC, NC, CT and TX.
Is there a charge for shipping?
Yes. Massey Drugs uses UPS for shipping.
- UPS Ground: $15
- UPS Next Day Air (end of day): $30
- UPS Next Day Air Early (by 10am): $100
Note: Early delivery is not available in all areas.
Next Steps
If you are interested in Semaglutide Sublingual Suspension, talk to your healthcare provider. Clinics interested in prescribing Semaglutide Sublingual can register for the Practitioner Portal for prescription blanks and pricing. Contact us to speak with a pharmacist.