Acetylcysteine Ophthalmic Solution (5% and 10%)

Acetylcysteine Ophthalmic Solution

Acetylcysteine 10% Ophthalmic Drops

Available Concentrations: 5% and 10%
Quantity:
10 mL

Price: Call 833.540.3500 or login to the Practitioner Portal for pricing.

Sterile compounded ophthalmic preparation available by prescription. The FDA does not review any compounded medication for safety or efficacy. 

What is Acetylcysteine Ophthalmic Solution?

Acetylcysteine ophthalmic solution is a compounded sterile eye drop available in multiple concentrations.

As a mucolytic, acetylcysteine works by disrupting the structure of mucus, making it less adhesive and easier to clear from the ocular surface. This can help reduce:

  • Mucus strand formation
  • Filament adherence to the cornea
  • Associated irritation and discomfort

Compounding allows for both 5% and 10% concentrations, which may be selected based on severity and patient tolerance.

What is the Mechanism of Action?

Acetylcysteine works by:

  • Breaking disulfide bonds within mucoproteins
  • Reducing mucus viscosity
  • Facilitating clearance of mucus from the ocular surface

This mechanism helps disrupt the formation of filaments that can adhere to the cornea and cause irritation, foreign body sensation, and epithelial disruption.

Clinical Scenarios Where Ophthalmologists Explore Acetylcysteine Eye Drops

Ophthalmologists may consider this compounded formulation in scenarios such as:

  • Filamentary keratitis
  • Dry eye disease with mucus strand formation
  • Ocular surface disease with abnormal tear film composition
  • Conditions associated with excessive or viscous mucus production
  • Patients requiring customized mucolytic therapy

Use is determined by the treating ophthalmologist based on severity, symptoms, and underlying condition.

Why Ophthalmologists Choose Massey Drugs

  • Sterile compounding laboratory experienced in ophthalmic preparations
  • Preservative-free formulations tailored for ocular use
  • Direct pharmacist access for clinical questions
  • Fast turnaround with patient shipment typically within 24–48 hours
  • Experience working with corneal specialists and surgical practices
  • NABP Accredited Compounding Pharmacy

States We Serve

States where Massey Drugs ships compounded medications.

Massey Drugs is a sterile ophthalmic compounding pharmacy licensed to ship ophthalmic solutions to patients in: Alabama, Tennessee, Mississippi, Louisiana, Georgia, Florida, North Carolina, South Carolina, Kentucky, Illinois, Indiana, Ohio, Pennsylvania, New York, Connecticut, and Texas.

How to Prescribe Acetylcysteine Ophthalmic Solution

Download Rx Blank from the Practitioner Portal and send to Massey Drugs:

FAX: 800.637.2601
Phone: 833.540.3500
OR

e-Scribe: NPI#: 1295756245 | NCPCP#: 0127553
Massey Drugs | Cloverdale Road 

Upon receipt of prescription, Massey Drugs contacts the patient to confirm shipping address and credit card payment. 

Medication ships to patient in 24-48 hours once processed.

Massey Drugs provides competitively priced compounded ophthalmic eye drops with transparent, prescriber-accessible pricing. All compound pricing can be viewed in our Practitioner Portal so costs can be communicated to patients before prescribing.

Speak with a Pharmacist

If you have questions about ophthalmic compounding, formulation options, or whether this therapy may be appropriate for a specific clinical scenario, our pharmacists are available to consult. Call 833-540-3500 or contact us.

Frequentley Asked Questions

When is 10% acetylcysteine chosen over 5%?

A higher concentration may be considered in more severe cases of filamentary keratitis or dense mucus formation, while lower concentrations may be used when tolerability is a concern.

Commercial ophthalmic formulations are not widely available, so compounding allows for customized concentrations and patient-specific treatment options.

Filamentary keratitis is often associated with dry eye disease, ocular surface inflammation, post-surgical states, and autoimmune conditions affecting tear production.

Additional Ophthalmic Compounding Capabilities

We compound additional sterile ophthalmic therapies used for: 

  • Post-operative Care
  • Emergency & Infection Management
  • Emergency & Corneal Scarring Support
  • Glaucoma Compounding
  • Myopia Management

Explore our full range of ophthalmic compounding capabilities.